Synthese van diketopiperazines als inhibitoren van histon deacetylase. (Gunther Roesems)


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Boc:  t-butoxycarbonyl

bs: breed singlet

Bzl: benzyl

COSY: homonucleaire correlatie spectroscopie

d: doublet

dd: dubbel doublet

DiPEA: diisopropylethylamine

DMAP: dimethylaminopyridine

DMF: dimethylformamide

DNA: desoxyribonucleïnezuur

eq.: equivalent

ES: electrospray

HPLC: High Pressure Liquid Chromatography

IR: infrarood spectroscopy

kt: kamertemperatuur

LC / MS: Liquid Chromatography / Mass Spectrometry

Lys: lysine

M: massief

m: multiplet

Me: methyl

MS: massaspectrometrie

m/z: massa/lading

NMR: Nuclear Magnetic Resonance

ppm: parts per million

Ph: fenyl

Phe: fenylalanine

psi: 1 bar = 14.5 psi

Rf: ratio to the front

Rt: retentietijd


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